- Any individual with a known or suspected family history of a genetic disease or condition
- Any couple who has experienced three or more spontaneous fetal losses
- Any couple who has experienced the birth of a child with multiple congenital anomolies of unexplained etiology
- Any consanguinous couple
- Any pregnancy known or suspected to be at risk for teratogenic exposure
- Any child with multiple congenital anomolies
- Any child with developmental delay, loss of milestones +/or seizures
- Any child with growth +/or sexual +/or developmental delay
- Any individual affected by or at risk for aneurogenetic disorder
- Any individual affect by or at risk for cancer known or suspected to have genetic etiology
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