Film Guide for:
Nick Nolte and Susan Sarandon
by Cathy Ross
Please read these questions over before you see the movie!! Then consider and write
your answers on your own paper.
© C. Sheils Ross, 1993
- From the description of the disease, ALD, (adrenoleukodystrophy) sketch what Lorenzo's
neurons most likely looked like after a year. Include a sketch of a normal neuron.
- ALD is a recessive sex-linked or X-linked disease. If this is a partial family
tree for the Odone's, what are the probable genotypes of the family members listed:
XA = normal neurons and xa = ALD
Aunt #1 . . . . X--X--
Aunt #2 . . . . X--X--
Aunt Dee . . . X--X--
Michaela . . . X--X--
Augusto . . . . X--Y
Lorenzo . . . . X--Y
- What was Augusto Odone's plumbing example used to explain? How do analogies often
help us understand a scientific problem?
- How did diet affect this disease's progression? And what was "Lorenzo's Oil" ?
Why was it so special?
- How did Augusto use modeling (paper clips) to solve a scientific problem? Can
you think of other "great discoveries" that employed models?
- Did this family's courage and persistence inspire you? How?
- Why did they encounter resistance from the medical community and from the support
organization? What did you learn from observing this behavior?
- We can learn anything we want to. Most of us will and should regard ourselves
as "lifelong learners." How did Augusto and Michaela Odone demonstrate this?
- As you reflect on this movie, how did the Odone family use the scientific method?
Start with the problem statement and use examples from the movie to illustrate
- How do we all use scientific method to solve everyday problems in our lives?